Peripartum COVID-19 vaccination is safe and beneficial for mothers and neonates
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Reviewed by Dat Tien Nguyen, B.A, ScM.
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Posted on October 10th, 2022
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Currently, very little is known about the effect COVID-19 vaccination has on pregnancy. Thus, many unreliable sources have claimed that immunization is unsafe for the mother’s and fetus’s health. A recent literature review published in the Journal of the American Medical Association had reported on the safety profile of COVID-19 vaccination on pregnancy.
The paper included data from 9 observational studies that had compared neonatal and maternal health outcomes of between a total of 81,349 women that were vaccinated during the pregnancy and 255,346 women that did not. The study found that peripartum COVID-19 vaccination was effective in preventing maternal SARS-CoV-2 infection by reducing the odds by 54%. In addition, immunization helps protect the newborn by reducing the odds of neonatal intensive care unit admission by 12% and intrauterine fetal death by 27%. More significantly, the study provides more insight into the safety profile of the vaccine, as the vaccine is not significantly associated with:
The paper included data from 9 observational studies that had compared neonatal and maternal health outcomes of between a total of 81,349 women that were vaccinated during the pregnancy and 255,346 women that did not. The study found that peripartum COVID-19 vaccination was effective in preventing maternal SARS-CoV-2 infection by reducing the odds by 54%. In addition, immunization helps protect the newborn by reducing the odds of neonatal intensive care unit admission by 12% and intrauterine fetal death by 27%. More significantly, the study provides more insight into the safety profile of the vaccine, as the vaccine is not significantly associated with:
- Chorioamnionitis
- Small fetus size
- Need for cesarean delivery
- Preterm birth
- Low APGAR score
- Postpartum hemorrhage